Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel gene variation of TNFalpha associated with ankylosing spondylitis: a reconfirmed study.

Annals of the rheumatic diseases - 1 Nov 2007

Zhu Xiaoquan, Wang Yawen, Sun Liang, Song Yuguo, Sun Fei, Tang Lei, Huo Zhenghao, Li Jianxin, Yang Ze

Abstract excerpt

BACKGROUND: A great deal of evidence has shown that non-human leucocyte antigen (HLA)-B27 genes may play crucial roles in the aetiology of ankylosing spondylitis (AS), but there is little evidence of a relationship with tumour necrosis factor (TNF)alpha gene variation. One functional single-nucleotide polymorphism (SNP), -850 C-->T, on the TNFalpha gene promoter region was identified and confirmed to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to HLA-B27 Antigen

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Spondylitis, Ankylosing

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 17472990
DOI: 10.1136/ard.2006.068528
PMCID: PMC2111619

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel gene variation of TNFalpha associated with ankylosing spondylitis: a reconfirmed study.PMID 17472990Read ↗

Re: Zhu et al, "A novel gene variation of TNF alpha associated with ankylosing spondylitis: a reconfirmed study".Semantic proximity Read ↗

The Associations of rs1799724 and rs361525 With the Risk of Ankylosing Spondylitis Are Dependent on HLA-B27 Status in a Chinese Han Population.Semantic proximity Read ↗

Associations of Tumor Necrosis Factor Alpha Gene Polymorphisms and Ankylosing Spondylitis Susceptibility: A Meta-analysis Based on 35 Case-control Studies.Semantic proximity Read ↗

Lack of association between TNF polymorphism and ankylosing spondylitis susceptibility in HLA-B27-positive population: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of tumor necrosis factor-α promoter region for susceptibility to HLA-B27-positive ankylosing spondylitis in Korean population.Semantic proximity Read ↗

The association of polymorphisms in TNF and ankylosing spondylitis in common population: a meta-analysis.Semantic proximity Read ↗

The association between TNF-alpha promoter polymorphisms and ankylosing spondylitis: a meta-analysis.Semantic proximity Read ↗

Role of TNFRSF1A and TNFRSF1B polymorphisms in susceptibility, severity, and therapeutic efficacy of etanercept in human leukocyte antigen-B27-positive Chinese Han patients with ankylosing spondylitis.Semantic proximity Read ↗

Three TNFalpha single nucleotide polymorphisms in the Japanese population.Semantic proximity Read ↗

TNF-α-308 polymorphism determines clinical manifestations and therapeutic response of ankylosing spondylitis in Han Chinese.Semantic proximity Read ↗

HLA-B27 subtypes and tumor necrosis factor alpha promoter region polymorphism in Iranian patients with ankylosing spondylitis.Semantic proximity Read ↗

Studies on correlation between single-nucleotide polymorphisms of tumor necrosis factor gene and different stages of ankylosing spondylitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.