Article
Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter.
Tissue antigens - 1 Oct 1998
Uglialoro A M, Turbay D, Pesavento P A, Delgado J C, McKenzie F E, Gribben J G, Hartl D, Yunis E J, Goldfeld A E
Abstract excerpt
We have identified three new human tumor necrosis factor-alpha (TNF-alpha) promoter polymorphisms with single nucleotide (nt) substitutions at -862, -856, and -574 nt relative to the TNF-alpha transcription start site. The -862 and -856 nt TNF-alpha promoter polymorphisms occur with high frequenc...
Topics
- Animals
- Base Sequence
- Cambodia
- Cell Line
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Linkage Disequilibrium
- Major Histocompatibility Complex
- Mice
- Molecular Sequence Data
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Tumor Cells, Cultured
