Article
Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter.
Tissue antigens - 1 Oct 1998
Uglialoro A M, Turbay D, Pesavento P A, Delgado J C, McKenzie F E, Gribben J G, Hartl D, Yunis E J, Goldfeld A E
Abstract excerpt
We have identified three new human tumor necrosis factor-alpha (TNF-alpha) promoter polymorphisms with single nucleotide (nt) substitutions at -862, -856, and -574 nt relative to the TNF-alpha transcription start site. The -862 and -856 nt TNF-alpha promoter polymorphisms occur with high frequency in Caucasian and Cambodian individuals and are each non-randomly associated with three extended HLA haplotypes. This...
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