Article
NcoI restriction fragment length polymorphism at -308 of the tumor necrosis factor alpha (TNFA) promoter region in Korean.
The Japanese journal of human genetics - 1 Mar 1997
Park K S, Kim M Y, Mok J W
Abstract excerpt
Tumor necrosis factor alpha (TNFA) is a cytokine, which is secreted from activated macrophage, with a broad range of biological activities. The gene encoding TNFA is located in tandem with the TNFB gene within the HLA complex on chromosome 6p21.3. We detected a single base polymorphism in the hum...
Topics
- Alleles
- Base Sequence
- Deoxyribonucleases, Type II Site-Specific
- Gene Frequency
- Genes
- Humans
- Korea
- Molecular Sequence Data
- Point Mutation
- Polymorphism, Restriction Fragment Length
- Promoter Regions, Genetic
- Tumor Necrosis Factor-alpha
