Article
NcoI restriction fragment length polymorphism at -308 of the tumor necrosis factor alpha (TNFA) promoter region in Korean.
The Japanese journal of human genetics - 1 Mar 1997
Park K S, Kim M Y, Mok J W
Abstract excerpt
Tumor necrosis factor alpha (TNFA) is a cytokine, which is secreted from activated macrophage, with a broad range of biological activities. The gene encoding TNFA is located in tandem with the TNFB gene within the HLA complex on chromosome 6p21.3. We detected a single base polymorphism in the human TNFA gene promoter region in 300 unrelated Korean individuals. The TNFA promoter region which showed a G to A...
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