Article
Influence of the STAT3 genetic variants in the susceptibility to psoriatic arthritis and Behcet's disease.
Human immunology - 1 Feb 2013
Cénit María Carmen, Ortego-Centeno Norberto, Raya Enrique, Callejas José L, García-Hernandez Francisco J, Castillo-Palma María Jesús, Fernandez-Sueiro J L, Magro Cesar, Solans Roser, Castañeda Santos, Camps Maite, Hidalgo Ana, Espinosa Gerard, González-Gay Miguel A, González-Escribano M F, Martín Javier
Abstract excerpt
OBJECTIVE: Signal-transducer and activator of transcription protein 3 (STAT3) gene encodes a transducer and transcription factor that plays an important role in many cellular processes such as cell growth, apoptosis and immune response. Several STAT3 genetic variants have been associated to different autoimmune diseases. Our aim was to reveal the possible STAT3 influence in other immune-mediated diseases such as...
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