Article
STAT4: a risk factor for type 1 diabetes?
Human immunology - 1 Oct 2008
Zervou Maria I, Mamoulakis Dimitrios, Panierakis Charalampos, Boumpas Dimitrios T, Goulielmos George N
Abstract excerpt
Genes and mechanisms involved in autoimmune diseases, affecting approximately 5% of human population, remain still obscure but there is accumulating evidence that common genetic factors might predispose to multiple autoimmune disorders. STAT4, a transcription factor transmitting signals induced by several key cytokines, has recently been identified as a genetic risk factor for rheumatoid arthritis (RA), systemic...
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