Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.

doi:10.1038/ng.688

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Article

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.

Nature genetics - 1 Nov 2010

Hüffmeier Ulrike, Uebe Steffen, Ekici Arif B, Bowes John, Giardina Emiliano, Korendowych Eleanor, Juneblad Kristina, Apel Maria, McManus Ross, Ho Pauline, Bruce Ian N, Ryan Anthony W, Behrens Frank, Lascorz Jesús, Böhm Beate, Traupe Heiko, Lohmann Jörg, Gieger Christian, Wichmann Heinz-Erich, Herold Christine, Steffens Michael, Klareskog Lars, Wienker Thomas F, Fitzgerald Oliver, Alenius Gerd-Marie, McHugh Neil J, Novelli Giuseppe, Burkhardt Harald, Barton Anne, Reis André

Abstract excerpt

Psoriatic arthritis (PsA) is an inflammatory joint disease that is distinct from other chronic arthritides and which is frequently accompanied by psoriasis vulgaris (PsV) and seronegativity for rheumatoid factor. We conducted a genome-wide association study in 609 German individuals with PsA (cases) and 990 controls with replication in 6 European cohorts including a total of 5,488 individuals. We replicated PsA...

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Identifiers

PMID: 20953186
DOI: 10.1038/ng.688
PMCID: PMC2981079

Genes

TRAF6

Variants

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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