Article
JAK1 rs310241 and JAK3 rs3008 Genotypes May Increase Susceptibility to Psoriasis: A Case Control Study.
Skin pharmacology and physiology - 1 Jan 2020
Sayed Khadiga S, El-Komy Mohamed H M, Shehata Hany, ElShazly Sarah H, El Desouky Eman D, Amr Khalda Sayed, ElAraby Nesma M, AlOrbani Aya M
Abstract excerpt
BACKGROUND: Janus kinases (JAKs) are a family of non-receptor protein tyrosine kinases that are expressed in a variety of tissues. Several JAK-controlled cytokine receptor pathways are incriminated in the initiation and progression of psoriasis. Genetic polymorphisms influencing JAK expression would be anticipated to have a great impact on disease activity. OBJECTIVE: The aim of the study was to evaluate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
