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Article

Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.

Arthritis and rheumatism - 1 Dec 2012

Hou Shengping, Yang Zhenglin, Du Liping, Jiang Zhengxuan, Shu Qinmeng, Chen Yuanyuan, Li Fuzhen, Zhou Qingyun, Ohno Shigeaki, Chen Rui, Kijlstra Aize, Rosenbaum James T, Yang Peizeng

Abstract excerpt

OBJECTIVE: To identify susceptibility loci for Behçet's disease (BD) and elucidate their functional role. METHODS: A genome-wide association study (GWAS) and functional studies were conducted. A total of 149 patients and 951 controls were enrolled in the initial GWAS, and 554 patients and 1,159 controls were enrolled in the replication study. Real-time polymerase chain reaction, luciferase reporter assay, and...

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Identifiers

PMID: 23001997
DOI: 10.1002/art.37708

Genes

STAT4

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