Article
Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris.
Annals of the rheumatic diseases - 1 Jun 2011
Bowes John, Eyre Steve, Flynn Edward, Ho Pauline, Salah Salma, Warren Richard B, Marzo-Ortega Helena, Coates Laura, McManus Ross, Ryan Anthony W, Kane David, Korendowych Eleanor, McHugh Neil, FitzGerald Oliver, Packham Jonathan, Morgan Ann W, Griffiths Christopher E M, Bruce Ian N, Worthington Jane, Barton Anne
Abstract excerpt
OBJECTIVE: There is great interest in the identification of genetic factors that differentiate psoriatic arthritis (PsA) from psoriasis vulgaris (PsV), as such discoveries could lead to the identification of distinct underlying aetiological pathways. Recent studies identified single nucleotide polymorphisms (SNPs) in the interleukin 13 (IL-13) gene region as risk factors for PsV. Further investigations in one of...
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