Article
PTPN22 -1123G > C polymorphism is associated with susceptibility to primary immune thrombocytopenia in Chinese population.
Platelets - 1 Jan 2013
Ge Jing, Li Huiyuan, Gu Dongsheng, Du Weiting, Xue Feng, Sui Tao, Xu Jianhui, Yang Renchi
Abstract excerpt
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by autoantibody-mediated platelet destruction. Multiple factors have been implicated in ITP pathogenesis, including T-lymphocyte dysfunctions. The protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gen...
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