Article
PTPN22 gene polymorphisms in autoimmune diseases with special reference to systemic lupus erythematosus disease susceptibility.
Journal of postgraduate medicine - 1 Jan 2000
Pradhan V, Borse V, Ghosh K
Abstract excerpt
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease. SLE is a result of one or more immune mechanisms, like autoantibody production, complement activation, multiple inflammation and immune complex deposition leading to organ tissue damage. SLE affected patients are susceptible to common and opportunistic infections. There are several reports suggesting that Mycobacterium tuberculosis infection...
Topics
- Genetic Predisposition to Disease
- Humans
- Lupus Erythematosus, Systemic
- Polymorphism, Genetic
- Protein Tyrosine Phosphatase, Non-Receptor Type 22
- Protein Tyrosine Phosphatases
