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Article

Protein tyrosine phosphatase PTPN22 in human autoimmunity.

Autoimmunity - 1 Sept 2007

Vang Torkel, Miletic Ana V, Bottini Nunzio, Mustelin Tomas

Abstract excerpt

The discovery that a single-nucleotide polymorphism (SNP) in lymphoid tyrosine phosphatase (LYP), encoded by the PTPN22 gene, is associated with type 1 diabetes (T1D) has now been verified by numerous studies and has been expanded to rheumatoid arthritis, juvenile rheumatoid arthritis (JRA), systemic lupus erythematosus, Graves' disease, generalized vitiligo and other human autoimmune diseases. In this paper, we...

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Source

Identifiers

PMID: 17729039
DOI: 10.1080/08916930701464897

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protein tyrosine phosphatase PTPN22 in human autoimmunity.PMID 17729039Read ↗

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