Article
R620W polymorphism of protein tyrosine phosphatase PTPN22 in Egyptian children and adolescents with systemic lupus erythematosus: relation to thyroid autoimmunity.
International journal of adolescent medicine and health - 1 Jan 2013
Hamza Rasha Tarif, Awwad Khaled S, Temsah Khaled A, Hamed Amira I
Abstract excerpt
BACKGROUND: Some studies showed associations of the minor T allele of the C1858T single nucleotide polymorphism (SNP) corresponding to the R620W amino acid substitution of protein tyrosine phosphatase (PTPN22) with multiple autoimmune diseases, including systemic lupus erythematosus (SLE). OBJECTIVES: To study the frequency of PTPN22 R620W polymorphism among Egyptian patients with SLE and to test the association...
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