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Article

<i>PTPN22</i>: Its role in SLE and autoimmunity

1 Jan 2007

Abstract excerpt

A functional variant of protein tyrosine phosphatase nonreceptor 22 (PTPN22) has recently been shown to be associated with multiple autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, type 1 diabetes, and autoimmune thyroid disease. In this review, we discuss the structure and function of this gene and its disease-associated polymorphisms. In addition, we review the studies...

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PMID: 18075792
DOI: 10.1080/08916930701510848

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