Article
Site-directed mutations in the Sindbis virus 6K protein reveal sites for fatty acylation and the underacylated protein affects virus release and virion structure.
Virology - 1 Mar 1990
Gaedigk-Nitschko K, Ding M X, Levy M A, Schlesinger M J
Abstract excerpt
A small hydrophobic polypeptide of 55 amino acids, noted as the 6K protein, is formed during processing of the polyprotein translated from the Sindbis virus subgenomic 26 S mRNA. In the accompanying paper we show that this 6K protein can be found in purified preparations of virions and that it is...
Topics
- Acylation
- Animals
- Base Sequence
- Cell Line
- Cells, Cultured
- Chick Embryo
- Fibroblasts
- Genes, Viral
- Kinetics
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Sindbis Virus
- Viral Plaque Assay
- Viral Proteins
- Virion
- Virus Replication