Article
Palmitoylation of Sindbis Virus TF Protein Regulates Its Plasma Membrane Localization and Subsequent Incorporation into Virions.
Journal of virology - 1 Feb 2017
Ramsey Jolene, Renzi Emily C, Arnold Randy J, Trinidad Jonathan C, Mukhopadhyay Suchetana
Abstract excerpt
Palmitoylation is a reversible, posttranslational modification that helps target proteins to cellular membranes. The alphavirus small membrane proteins 6K and TF have been reported to be palmitoylated and to positively regulate budding. 6K and TF are isoforms that are identical in their N termini but unique in their C termini due to a -1 ribosomal frameshift during translation. In this study, we used cysteine...
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