Article
Characterization of revertants of a Sindbis virus 6K gene mutant that affects proteolytic processing and virus assembly.
Virus research - 1 Dec 1995
Ivanova L, Le L, Schlesinger M J
Abstract excerpt
Alphaviruses of the Togaviridae encode a small hydrophobic polypeptide of 55 amino acids, noted as the 6K protein, that is synthesized as part of a polyprotein containing the sequences of the two major transmembranal viral structural glycoproteins. Mutations, insertions and deletions in the 6K ap...
Topics
- Animals
- Base Sequence
- Cell Line
- Chick Embryo
- Chromosome Mapping
- Cricetinae
- DNA, Viral
- Endopeptidases
- Gene Expression Regulation, Viral
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation