Article
Characterization of revertants of a Sindbis virus 6K gene mutant that affects proteolytic processing and virus assembly.
Virus research - 1 Dec 1995
Ivanova L, Le L, Schlesinger M J
Abstract excerpt
Alphaviruses of the Togaviridae encode a small hydrophobic polypeptide of 55 amino acids, noted as the 6K protein, that is synthesized as part of a polyprotein containing the sequences of the two major transmembranal viral structural glycoproteins. Mutations, insertions and deletions in the 6K appear to selectively interfere with the final stages of virus assembly and budding, producing aberrant, multi-cored...
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