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Article

DNA methyltransferase 3b is dispensable for mouse neural crest development.

PloS one - 1 Jan 2012

Jacques-Fricke Bridget T, Roffers-Agarwal Julaine, Gammill Laura S

Abstract excerpt

The neural crest is a population of multipotent cells that migrates extensively throughout vertebrate embryos to form diverse structures. Mice mutant for the de novo DNA methyltransferase DNMT3b exhibit defects in two neural crest derivatives, the craniofacial skeleton and cardiac ventricular septum, suggesting that DNMT3b activity is necessary for neural crest development. Nevertheless, the requirement for...

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Identifiers

PMID: 23094090
DOI: 10.1371/journal.pone.0047794
PMCID: PMC3475715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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