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Article

Animal models for studying neural crest development: is the mouse different?

Development (Cambridge, England) - 1 May 2015

Barriga Elias H, Trainor Paul A, Bronner Marianne, Mayor Roberto

Abstract excerpt

The neural crest is a uniquely vertebrate cell type and has been well studied in a number of model systems. Zebrafish, Xenopus and chick embryos largely show consistent requirements for specific genes in early steps of neural crest development. By contrast, knockouts of homologous genes in the mouse often do not exhibit comparable early neural crest phenotypes. In this Spotlight article, we discuss these...

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Identifiers

PMID: 25922521
DOI: 10.1242/dev.121590
PMCID: PMC6514397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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