Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neural crest stem cell multipotency requires Foxd3 to maintain neural potential and repress mesenchymal fates.

Development (Cambridge, England) - 1 Feb 2011

Mundell Nathan A, Labosky Patricia A

Abstract excerpt

Neural crest (NC) progenitors generate a wide array of cell types, yet molecules controlling NC multipotency and self-renewal and factors mediating cell-intrinsic distinctions between multipotent versus fate-restricted progenitors are poorly understood. Our earlier work demonstrated that Foxd3 is required for maintenance of NC progenitors in the embryo. Here, we show that Foxd3 mediates a fate restriction choice...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Embryo, Mammalian
Share to Forkhead Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Multipotent Stem Cells

Share to Neural Crest

Share to Neural Stem Cells

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21228004
DOI: 10.1242/dev.054718
PMCID: PMC3026411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neural crest stem cell multipotency requires Foxd3 to maintain neural potential and repress mesenchymal fates.PMID 21228004Read ↗

Requirement for Foxd3 in the maintenance of neural crest progenitors.Semantic proximity Read ↗

Cranial neural crest cell contribution to craniofacial formation, pathology, and future directions in tissue engineeringSemantic proximity Read ↗

Multipotentiality of the neural crest.Semantic proximity Read ↗

Genetic ablation of neural crest cell diversification.Semantic proximity Read ↗

Neural crest-like stem cells for tissue regenerationSemantic proximity Read ↗

FGF8 signaling sustains progenitor status and multipotency of cranial neural crest-derived mesenchymal cells in vivo and in vitro.Semantic proximity Read ↗

The neural crest: Basic biology and clinical relationships in the craniofacial and enteric nervous systemsSemantic proximity Read ↗

Transcriptome profiling of the cardiac neural crest reveals a critical role for MafBSemantic proximity Read ↗

Neural Crest Cell Lineage Restricts Skeletal Muscle Progenitor Cell Differentiation through Neuregulin1-ErbB3 SignalingSemantic proximity Read ↗

Human neural crest cells display molecular and phenotypic hallmarks of stem cells.Semantic proximity Read ↗

Single-cell transcriptomic landscape of cardiac neural crest cell derivatives during embryonic and neonatal developmentSemantic proximity Read ↗

Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.