Article
Generation and characterization of a tamoxifen inducible Msx1(CreERT2) knock-in allele.
Genesis (New York, N.Y. : 2000) - 1 Feb 2013
Lallemand Yvan, Moreau Julie, Cloment Cécile Saint, Vives Francina Langa, Robert Benoît
Abstract excerpt
Msx1, a member of the Msx gene family, encodes a homeodomain transcription factor and plays critical roles during mouse development in numerous organs. By homologous recombination, we generated a new Msx1 allele (Msx1(CreERT2) ) in which the CreERT2 fusion protein is produced in place of the endogenous Msx1 protein. Using different reporter mouse strains and appropriate tamoxifen treatments, we show that, in mice...
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