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Article

Generating tamoxifen-inducible Cre alleles to investigate myogenesis in mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Lepper Christoph, Fan Chen-Ming

Abstract excerpt

Gene inactivation has become the gold standard for determining gene function in the mouse. Many genes inactivated in the germ line cause early lethality that precludes phenotypic assessment at a later time point. Conditional gene inactivation using Cre recombinase expressed via a tissue specific promoter/enhancer allows phenotypic analyses of selected tissues, but lacks temporal control. Recent development of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22130844
DOI: 10.1007/978-1-61779-343-1_17
PMCID: PMC3695624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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