Article
Generation of an Msx2-GFP conditional null allele.
Genesis (New York, N.Y. : 2000) - 1 May 2008
Bensoussan Vardina, Lallemand Yvan, Moreau Julie, Cloment Cécile Saint, Langa Francina, Robert Benoît
Abstract excerpt
Msx1 and Msx2, two members of the Msx gene family, encode homeoprotein transcription factors and play critical roles during mouse development. Because of the redundancy between the two genes, many of these roles can only be studied in double Msx1; Msx2 mutants. However, these animals die around 14.5 dpc, which precludes analysis of Msx gene function beyond this stage. Moreover, the pleiotropic defects displayed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.