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Article

Msx1CreERT2 knock-In allele: A useful tool to target embryonic and adult cardiac valves.

Genesis (New York, N.Y. : 2000) - 1 May 2015

Papoutsi Tania, Odelin Gaëlle, Moore-Morris Thomas, Pucéat Michel, de la Pompa José Luis, Robert Benoît, Zaffran Stéphane

Abstract excerpt

Heart valve development begins with the endothelial-to-mesenchymal transition (EMT) of endocardial cells. Although lineage studies have demonstrated contributions from cardiac neural crest and epicardium to semilunar and atrioventricular (AV) valve formation, respectively, most valve mesenchyme derives from the endocardial EMT. Specific Cre mouse lines for fate-mapping analyses of valve endocardial cells are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25950518
DOI: 10.1002/dvg.22856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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