Article
Conditional alleles of Msx1 and Msx2.
Genesis (New York, N.Y. : 2000) - 1 Aug 2007
Fu Hualin, Ishii Mamoru, Gu Ying, Maxson Robert
Abstract excerpt
The msh-related homeobox genes, Msx1 and Msx2, have a variety functions during murine organogenesis, Msx1 in the development of the palate and teeth, Msx2 in the skull, teeth, and skin. Msx1 mutants die perinatally. Compound Msx1-2 mutants do not survive past late gestation. The multiplicity of functions of Msx1 and 2, as well as the lethality of Msx1 and Msx1-2 mutants limits the utility of the conventional...
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