Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development.

doi:10.1038/ng0494-348

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Article

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development.

Nature genetics - 1 Apr 1994

Satokata I, Maas R

Abstract excerpt

The Msx1 homeobox gene is expressed at diverse sites of epithelial-mesenchymal interaction during vertebrate embryogenesis, and has been implicated in signalling processes between tissue layers. To determine the phenotypic consequences of its deficiency, we prepared mice lacking Msx1 function. Al...

Topics

Abnormalities, Multiple
Animals
Base Sequence
Cell Line
Chimera
Cleft Palate
DNA-Binding Proteins
Dental Papilla
Disease Models, Animal
Embryo Transfer
Embryonic Induction
Facial Bones
Female
Genes, Homeobox
Genes, Lethal
Genes, Recessive
Head
Homeodomain Proteins

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