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Article

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development.

Nature genetics - 1 Apr 1994

Satokata I, Maas R

Abstract excerpt

The Msx1 homeobox gene is expressed at diverse sites of epithelial-mesenchymal interaction during vertebrate embryogenesis, and has been implicated in signalling processes between tissue layers. To determine the phenotypic consequences of its deficiency, we prepared mice lacking Msx1 function. All Msx1- homozygotes manifest a cleft secondary palate, a deficiency of alveolar mandible and maxilla and a failure of...

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Identifiers

PMID: 7914451
DOI: 10.1038/ng0494-348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development.PMID 7914451Read ↗

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