Article
Haplotype study of the CYP4A11 gene and coronary artery disease in Han and Uygur populations in China.
Gene - 10 Jan 2013
Fu Zhenyan, Yang Hong, Ma Yitong, Huang Ding, Xie Xiang, Zheng Yingying, Zhu Qing, Nakayama Tomohiro
Abstract excerpt
BACKGROUND: CYP4A11 converts arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), which has a crucial role in the modulation of cardiovascular homeostasis. We assessed the association between the human CYP4A11 gene and coronary artery disease (CAD) in Han and Uygur populations in China. METHODS AND RESULTS: In the Han population, 361 CAD patients and 315 controls were genotyped for four...
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