Article
Relationship between CYP17A1 genetic polymorphism and coronary artery disease in a Chinese Han population.
Lipids in health and disease - 7 Mar 2015
Dai Chuan-Fang, Xie Xiang, Yang Yi-Ning, Li Xiao-Mei, Zheng Ying-Ying, Fu Zhen-Yan, Liu Fen, Chen Bang-Dang, Gai Min-Tao, Ma Yi-Tong
Abstract excerpt
BACKGROUND: CYP17A1 gene encodes P450c17 proteins, which is a key enzyme that catalyzes the formation of sex hormones. Many clinical studies showed that sex hormones levels play an important role in the pathogenesis of coronary artery disease (CAD). However, the relationship between CYP17A1 genetic polymorphisms and CAD remains unclear. The aim of this study was to investigate the association of CYP17A1 genetic...
Topics
- Asian People
- Case-Control Studies
- China
- Coronary Artery Disease
- Female
- Genes, Dominant
- Genes, Recessive
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide