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Article

Genetic variants in CYP11B1 influence the susceptibility to coronary heart disease.

BMC medical genomics - 13 Jul 2022

Huang Xiaoli, Cheng Yimin, Wang Na

Abstract excerpt

BACKGROUND: Genetic factors are important risk factors to develop coronary heart disease (CHD). In this study, we mainly explored whether CYP11B1 mutations influence CHD risk among Chinese Han population. METHODS: Six variants were genotyped using Agena MassARRAY system from 509 CHD patients and 509 healthy controls. The correlations between CYP11B1 mutations and CHD risk were assessed using odds ratio (OR) and...

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Identifiers

PMID: 35831903
DOI: 10.1186/s12920-022-01307-8
PMCID: PMC9281100

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