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Article

A Novel Polymorphism in the Promoter of the CYP4A11 Gene Is Associated with Susceptibility to Coronary Artery Disease.

Disease markers - 1 Jan 2018

Sirotina Svetlana, Ponomarenko Irina, Kharchenko Alexander, Bykanova Marina, Bocharova Anna, Vagaytseva Kseniya, Stepanov Vadim, Churnosov Mikhail, Solodilova Maria, Polonikov Alexey

Abstract excerpt

Enzymes CYP4A11 and CYP4F2 are involved in biosynthesis of vasoactive 20-hydroxyeicosatetraenoic acid and may contribute to pathogenesis of coronary artery disease (CAD). We investigated whether polymorphisms of the CYP4A11 and CYP4F2 genes are associated with the risk of CAD in Russian population. DNA samples from 1323 unrelated subjects (637 angiographically confirmed CAD patients and 686 age- and sex-matched...

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Identifiers

PMID: 29484037
DOI: 10.1155/2018/5812802
PMCID: PMC5816861

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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