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Article

Haplotype-based case-control study of CYP4A11 gene and myocardial infarction.

Hereditas - 1 Jun 2012

Fu Zhenyan, Nakayama Tomohiro, Sato Naoyuki, Izumi Yoichi, Kasamaki Yuji, Shindo Atsushi, Ohta Masakatsu, Soma Masayoshi, Aoi Noriko, Sato Mikano, Ozawa Yukio, Ma Yitong

Abstract excerpt

CYP4A11, which is a member of the cytochrome P450 family, acts mainly as an enzyme that converts arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite involved in the maintenance of cardiovascular health. Recently, it was reported that many subfamilies of CYP genes have an association with myocardial infarction (MI). The aim of the present study was to assess the association between the...

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PMID: 22804341
DOI: 10.1111/j.1601-5223.2012.02247.x

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