Article
PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population.
Oncotarget - 3 Jan 2017
Zhao Qingbin, Wei Huiyi, Liu Dandan, Shi Baolan, Li Lei, Yan Mengdan, Zhang Xiyang, Wang Fengjiao, Ouyang Yongri
Abstract excerpt
Previous studies showed that PHACTR1 and SLC22A3 are involved in coronary vascular development and are key determinants of cardiovascular disease risk. We conducted a case-control study to examine the effect of SLC22A3 and PHACTR1 single nucleotide polymorphisms (SNPs) on CAD risk among 376 male CAD patients and 388 male healthy controls from China. Eleven SLC22A3 and PHACTR1 SNPs were selected and genotyped...
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