Article
Haplotype analyses of CYP17A1 genetic polymorphisms and coronary artery disease in a Uygur population.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2015
Dai Chuan-Fang, Xie Xiang, Ma Yi-Tong, Yang Yi-Ning, Li Xiao-Mei, Fu Zhen-Yan, Liu Fen, Chen Bang-Dang, Gai Min-Tao
Abstract excerpt
BACKGROUND: The relationship between CYP17A1 genetic polymorphisms and coronary artery disease (CAD) remains unclear. The aim of the present study was to assess the association between CYP17A1 gene polymorphism and CAD in a Chinese Uygur population. METHODS: A total of 493 people including 266 patients and 227 controls were selected for the present study. All CAD patients and controls were genotyped for the same...
Topics
- Case-Control Studies
- Coronary Artery Disease
- Demography
- Ethnicity
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Linkage Disequilibrium
- Logistic Models
- Male
- Middle Aged