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Article

Selective brain gray matter atrophy associated with APOE ε4 and MAPT H1 in subjects with mild cognitive impairment.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Goñi Joaquín, Cervantes Sebastián, Arrondo Gonzalo, Lamet Isabel, Pastor Pau, Pastor María A

Abstract excerpt

The aim of our study was to elucidate whether specific patterns of gray matter loss were associated with apolipoprotein E ε4 (APOE ε4) and microtubule-associated protein tau (MAPT)-H1) genetic variants in subjects with mild cognitive impairment (MCI) at a baseline visit. Gray matter voxel-based morphometry analysis of T1 magnetic resonance imaging scans were performed in 65 amnestic-MCI subjects. MCI APOE ε4...

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Source

Identifiers

PMID: 23064258
DOI: 10.3233/JAD-2012-121174

Genes

APOE
MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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