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Article

Cohesinopathies, gene expression, and chromatin organization.

The Journal of cell biology - 19 Apr 2010

Bose Tania, Gerton Jennifer L

Abstract excerpt

The cohesin protein complex is best known for its role in sister chromatid cohesion, which is crucial for accurate chromosome segregation. Mutations in cohesin proteins or their regulators have been associated with human diseases (termed cohesinopathies). The developmental defects observed in these diseases indicate a role for cohesin in gene regulation distinct from its role in chromosome segregation. In...

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Identifiers

PMID: 20404106
DOI: 10.1083/jcb.200912129
PMCID: PMC2856913

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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