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Article

Genetic schizophrenia risk variants jointly modulate total brain and white matter volume.

Biological psychiatry - 15 Mar 2013

Terwisscha van Scheltinga Afke F, Bakker Steven C, van Haren Neeltje E M, Derks Eske M, Buizer-Voskamp Jacobine E, Boos Heleen B M, Cahn Wiepke, Hulshoff Pol Hilleke E, Ripke Stephan, Ophoff Roel A, Kahn René S

Abstract excerpt

BACKGROUND: Thousands of common single nucleotide polymorphisms (SNPs) are weakly associated with schizophrenia. It is likely that subsets of disease-associated SNPs are associated with distinct heritable disease-associated phenotypes. Therefore, we examined the shared genetic susceptibility modulating schizophrenia and brain volume. METHODS: Odds ratios for genome-wide SNP data were calculated in the sample...

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Identifiers

PMID: 23039932
DOI: 10.1016/j.biopsych.2012.08.017
PMCID: PMC3573254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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