Article
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness.
JAMA psychiatry - 1 Sept 2021
Cheng Weiqiu, Frei Oleksandr, van der Meer Dennis, Wang Yunpeng, O'Connell Kevin S, Chu Yunhan, Bahrami Shahram, Shadrin Alexey A, Alnæs Dag, Hindley Guy F L, Lin Aihua, Karadag Naz, Fan Chun-Chieh, Westlye Lars T, Kaufmann Tobias, Molden Espen, Dale Anders M, Djurovic Srdjan, Smeland Olav B, Andreassen Ole A
Abstract excerpt
Importance: Schizophrenia is a complex heritable disorder associated with many genetic variants, each with a small effect. While cortical differences between patients with schizophrenia and healthy controls are consistently reported, the underlying molecular mechanisms remain elusive. Objective: To investigate the extent of shared genetic architecture between schizophrenia and brain cortical surface area (SA) and...
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