Article
Heritability of changes in brain volume over time in twin pairs discordant for schizophrenia.
Archives of general psychiatry - 1 Nov 2008
Brans Rachel G H, van Haren Neeltje E M, van Baal G Caroline M, Schnack Hugo G, Kahn René S, Hulshoff Pol Hilleke E
Abstract excerpt
CONTEXT: Structural brain abnormalities have consistently been found in schizophrenia, with increased familial risk for the disease associated with these abnormalities. Some brain volume changes are progressive over the course of the illness. Whether these progressive brain volume changes are mediated by genetic or disease-related factors is unknown. OBJECTIVE: To investigate whether genetic and/or environmental...
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