Article
Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1.
Schizophrenia bulletin - 1 Jan 2019
Chen Jiayu, Calhoun Vince D, Lin Dongdong, Perrone-Bizzozero Nora I, Bustillo Juan R, Pearlson Godfrey D, Potkin Steven G, van Erp Theo G M, Macciardi Fabio, Ehrlich Stefan, Ho Beng-Choon, Sponheim Scott R, Wang Lei, Stephen Julia M, Mayer Andrew R, Hanlon Faith M, Jung Rex E, Clementz Brett A, Keshavan Matcheri S, Gershon Elliot S, Sweeney John A, Tamminga Carol A, Andreassen Ole A, Agartz Ingrid, Westlye Lars T, Sui Jing, Du Yuhui, Turner Jessica A, Liu Jingyu
Abstract excerpt
Genetic factors are known to influence both risk for schizophrenia (SZ) and variation in brain structure. A pressing question is whether the genetic underpinnings of brain phenotype and the disorder overlap. Using multivariate analytic methods and focusing on 1,402 common single-nucleotide polymorphisms (SNPs) mapped from the Psychiatric Genomics Consortium (PGC) 108 regions, in 777 discovery samples, we...
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