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Article

Genetic variants of p21 and p27 and hepatocellular cancer risk in a Chinese Han population: a case-control study.

International journal of cancer - 1 May 2013

Liu Fei, Wei Yong-Gang, Luo Li-Mei, Wang Wen-Tao, Yan Lv-Nan, Wen Tian-Fu, Xu Ming-Qing, Yang Jia-Yin, Li Bo

Abstract excerpt

The p21 (Cip1/CDKN1A) and p27 (Kip1/CDKN1B) are members of the Cip/Kip family of cyclin-dependent kinase inhibitors, which can arrest cell proliferation and serve as tumour suppressors. We hypothesized that genetic variants in p21 and p27 may modify individual susceptibility to hepatocellular carcinoma (HCC). To test this hypothesis, we evaluated the associations of the polymorphisms of Ser31Arg and C+20T in p21...

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Identifiers

PMID: 23034899
DOI: 10.1002/ijc.27885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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