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Article

Polymorphisms in the 5' upstream regulatory region of p21(WAF1/CIP1) and susceptibility to oesophageal squamous cell carcinoma.

Scientific reports - 2 Mar 2016

Yang Wenjun, Li Yong, Ning Tao, Cai Hong, Chen Zhiqiang, Dong Ying, Ke Yang

Abstract excerpt

This study aims to scan the 5'-upstream regulatory region of the p21 gene to identify all putative functional single nucleotide polymorphisms (SNPs) and to evaluate the contribution of p21 variants to oesophageal squamous cell carcinoma (ESCC) in the Chinese Han population. Common SNPs were identified, and both locus-based and haplotype-based association tests were used to evaluate the potential risk of these p21...

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Source

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Identifiers

PMID: 26932598
DOI: 10.1038/srep22564
PMCID: PMC4773838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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