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Article

Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients.

Human genetics - 1 Feb 1990

Fukuchi K, Tanaka K, Kumahara Y, Marumo K, Pride M B, Martin G M, Monnat R J

Abstract excerpt

The frequency of spontaneous 6-thioguanine (TG)-resistant peripheral blood lymphocytes in five unrelated Werner syndrome (WS) patients was determined using an autoradiographic labeling assay. The average frequency of TG-resistant lymphocytes was eightfold higher in WS patients than in sex- and age-matched normal control donors. This finding and previous identification of increased spontaneous chromosomal...

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Identifiers

PMID: 2303247
DOI: 10.1007/BF00200569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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