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Article

Enhanced 2-deoxy-D-ribose-induced-apoptosis, a phenotype of lymphocytes from old donors, is not observed in the Werner syndrome.

Experimental gerontology - 1 Aug 2000

Battisti C, Formichi P, Tripodi S A, Morbini G, Tosi P, Federico A

Abstract excerpt

Werner syndrome (WS) is an inherited disease characterized by the premature appearance of features of normal aging in young adults. To evaluate the relationship between Werner syndrome and aging, we analyzed the apoptotic response of peripheral blood lymphocytes (PBLs) from two WS patients (mean age 34 years old) incubated with 2-deoxy-D-ribose (dRib), a reducing sugar that induces apoptosis in quiescent cells...

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Identifiers

PMID: 10978682
DOI: 10.1016/s0531-5565(00)00099-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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