Article
Detection of 6-thioguanine-resistant spleen lymphocytes in different mouse strains by autoradiography.
Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1991
Hüttner E, Braun R, Wielgosz S M, Schöneich J
Abstract excerpt
The variant frequencies for 6-thioguanine-resistant spleen cells in different mouse strains have been estimated by autoradiography for animals without chemical treatment and in cases of in vivo mutagen dosage with ethylnitrosourea and cyclophosphamide, respectively. In untreated mice, the following variant frequencies have been found: C57Bl/6J, 2.84 x 10(-5);NMRI, 3.04 x 10(-5);DBA/2J, 5.91 x 10(-5). The...
Topics
- Animals
- Autoradiography
- Cyclophosphamide
- Ethylnitrosourea
- Female
- Lymphocytes
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mutation
- Spleen
