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Article

CRISPR/Cas9 mediated multiplex genome editing and heritable mutagenesis of BmKu70 in Bombyx mori.

Scientific reports - 27 Mar 2014

Ma Sanyuan, Chang Jiasong, Wang Xiaogang, Liu Yuanyuan, Zhang Jianduo, Lu Wei, Gao Jie, Shi Run, Zhao Ping, Xia Qingyou

Abstract excerpt

CRISPR/Cas9, a bacterial adaptive immune system derived genome-editing technique, has become to be one of the most compelling topics in biotechnology. Bombyx mori is an economically important insect and a model organism for studying lepidopteran and arthropod biology. Here we reported highly efficient and multiplex genome editing in B. mori cell line and heritable site-directed mutagenesis of Bmku70, which is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24671069
DOI: 10.1038/srep04489
PMCID: PMC3967148

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Source receipt: pubmed, retrieved 7 Sept 2026.

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