Article
An essential role of variant histone H3.3 for ectomesenchyme potential of the cranial neural crest.
PLoS genetics - 1 Sept 2012
Cox Samuel G, Kim Hyunjung, Garnett Aaron Timothy, Medeiros Daniel Meulemans, An Woojin, Crump J Gage
Abstract excerpt
The neural crest (NC) is a vertebrate-specific cell population that exhibits remarkable multipotency. Although derived from the neural plate border (NPB) ectoderm, cranial NC (CNC) cells contribute not only to the peripheral nervous system but also to the ectomesenchymal precursors of the head skeleton. To date, the developmental basis for such broad potential has remained elusive. Here, we show that the...
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