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CHD3 regulates BMP signalling response during cranial neural crest cell specification

2025-02-14

Abstract excerpt

<h4>Summary</h4> CHD3 is a component of the NuRD chromatin remodeling complex. Pathogenic CHD3 variants cause Snijders Blok-Campeau Syndrome, a neurodevelopmental disorder with variable features including developmental delays, intellectual disability, speech/language difficulties, and craniofacial anomalies. To unveil the role of CHD3 in craniofacial development, we differentiated CHD3 -KO induced pluripotent s...

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Literature Corpus work
3a9c2bc3-5867-5f1e-80e4-ce3f1ec36c42
DOI
10.1101/2025.02.14.638260
Open publication

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CHD3 regulates BMP signalling response during cranial neural crest cell specificationDOI 10.1101/2025.02.14.638260
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