Article
Mechanisms and consequences of mutation induction in mammalian cells.
International journal of radiation biology - 1 Apr 1990
Sarasin A, Bourre F, Daya-Grosjean L, Gentil A, Madzak C, Stary A
Abstract excerpt
Mutations have been studied for several decades in order to understand biological processes of great significance and the selection of better-adapted species. Our knowledge both of mutation spectra induced by genotoxic agents and the mechanisms involved in DNA damage processing is more advanced in bacteria than in animal cells. However, the use of new technologies such as shuttle vectors or the polymerase chain...
Topics
- Animals
- Humans
- In Vitro Techniques
- Mutagens
- Mutation
- Neoplasms
- Proto-Oncogenes
- Ultraviolet Rays
