tagSNP rs1495741 as a useful molecular marker to predict antituberculosis drug-induced hepatotoxicity.

doi:10.1097/FPC.0000000000000224

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Article

tagSNP rs1495741 as a useful molecular marker to predict antituberculosis drug-induced hepatotoxicity.

Pharmacogenetics and genomics - 1 Jul 2016

Chamorro Julián G, Castagnino Jorge P, Musella Rosa M, Nogueras Mabel, Frías Ana, Visca Mabel, Aidar Omar, Costa Lucas, de Larrañaga Gabriela F

Abstract excerpt

INTRODUCTION: It has been widely reported that the slow acetylator phenotype of N-acetyltransferase 2 (NAT2) is associated with the development of antituberculosis drug-induced hepatotoxicity (ATDH). The aim of this report was to evaluate the level of agreement and accuracy of two recently recommended markers, the two-single nucleotide polymorphisms (SNP) (C282T and T341C) and tagSNP of NAT2 (rs1495741)...

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Share to Acetylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Arylamine N-Acetyltransferase

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Identifiers

PMID: 27104815
DOI: 10.1097/FPC.0000000000000224

Genes

NAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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