Article
Association of N-acetyltransferase-2 genotypes and anti-tuberculosis induced liver injury; first case-controlled study from Iran.
Current drug safety - 1 Feb 2011
Khalili Hossein, Fouladdel Shamileh, Sistanizad Mohammad, Hajiabdolbaghi Mahboobeh, Azizi Ebrahim
Abstract excerpt
PURPOSE: The goals of this study were to identify the frequency of N-acetyltransferase-2 genotypes and phenotypes in Iranian tuberculosis and healthy subjects and to evaluate correlation of acetylator phenotype and antituberculosis-induced hepatotoxicity in pulmonary tuberculosis patients. METHOD: A total of 50 newly diagnosed pulmonary tuberculosis patients and 50 healthy Iranian subjects were enrolled in the...
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